Jed L. Hubbs, PhD
Jed L. Hubbs, PhD is a medicinal chemist and drug discovery scientist at Boston Children's Hospital and Harvard Medical School. He leads the Hubbs Lab within the Translational Neuroscience Center, where his group focuses on discovering treatments for rare neurodevelopmental disorders.
Before transitioning to academia, Dr. Hubbs spent over a decade in the pharmaceutical industry, leading drug discovery programs from target hypothesis through IND-enabling studies. His industry experience includes scientific leadership roles at Satori Pharmaceuticals and EnVivo Pharmaceuticals, where he advanced programs in neurology from screening hits to preclinical development candidates.
His academic training includes a PhD in Chemistry from UC Berkeley (total synthesis with Clayton Heathcock) and postdoctoral work at Harvard (enantioselective catalysis with David Evans). This combination of synthetic chemistry expertise and pharmaceutical development experience informs his lab's approach to academic drug discovery.
Dr. Hubbs' lab brings an industry mindset to rare disease research: rigorous assay development in patient-derived iPSC neurons, phenotypic screening with medicinal chemistry follow-up, and a portfolio approach that advances multiple programs in parallel.